PolyPhen-2 prediction of functional effects of human nsSNPs

PolyPhen-2 report for P00441 V6L

Query

Protein AccPositionAA1AA2Description
P004416VLRecName: Full=Superoxide dismutase [Cu-Zn]; EC=1.15.1.1; LENGTH: 154 AA

Results

Prediction/Confidence  PolyPhen-2 v2.0.23r349

HumDiv

This mutation is predicted to be possibly damaging with a score of 0.517 (sensitivity: 0.87; specificity: 0.87)

Confidence

HumVar

Details

Multiple sequence alignment  UniProtKB/UniRef100 Release 2010_11 (02-Nov-2010)
3D Visualization  PDB/DSSP Snapshot 09-Nov-2010 (69162 Structures)