PolyPhen-2 prediction of functional effects of human nsSNPs

PolyPhen-2 report for P00441 V48A

Query

Protein AccPositionAA1AA2Description
P0044148VARecName: Full=Superoxide dismutase [Cu-Zn]; EC=1.15.1.1; LENGTH: 154 AA

Results

Prediction/Confidence  PolyPhen-2 v2.1.0r367

HumDiv

This mutation is predicted to be probably damaging with a score of 1.000 (sensitivity: 0.00; specificity: 1.00)

Confidence

HumVar

Details

Multiple sequence alignment  UniProtKB/UniRef100 Release 2011_04 (05-Apr-2011)
3D Visualization  PDB/DSSP Snapshot 06-Apr-2011 (72244 Structures)